National Antimicrobial Resistance Monitoring System (NARMS) Strategic Plan 2012-2016.

摘要

The National Antimicrobial Resistance Monitoring System (NARMS), established in 1996, is a collaboration among the U.S. Food and Drug Administration (FDA), the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Department of Agriculture (USDA), and state and local health departments. NARMS monitors antimicrobial susceptibility in enteric bacteria from humans, retail meats and food-producing animals. In addition to monitoring, NARMS conducts epidemiologic and microbiologic research studies. Some studies examine risk factors and clinical outcomes of infections with specific bacterial serotypes or subsets of bacteria that exhibit particular resistance patterns. Microbiological research studies focus on understanding the genetic mechanisms of antimicrobial resistance in enteric bacteria and the mechanisms that permit the transfer of resistance between bacteria, on improving methods for isolation and typing, and on developing new methods for antimicrobial susceptibility testing. Additionally, NARMS examines enteric bacteria for genetic interrelatedness using methods such as pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST).