Coordinating Center Models Project: A Study of Coordinating Centers in Multicenter Clinical Trials. XIV. Enhancement of Methodological Research in the Field of Clinical Trials

摘要

Research and development are needed to improve the design, organization, and operation of clinical trials. To date, such efforts have not been sufficient to keep pace with the expanding needs of the field. Reasons for this deficiency may be a lack of identity for the field of clinical trials and passive attitudes towards methodology, both by investigators who participate in clinical trials and agencies who sponsor them. This report focuses on measures which can be taken by investigators and sponsors to increase the amount and scope of methodological and developmental activities in clinical trials and to enhance the communication of methodological information for the field.