Hostility and Anger in Women with Suspected Coronary Artery Disease: The Women's Ischemia Syndrome Evaluation (WISE) Study

摘要

This study reports analyses from the Women s Ischemia Syndrome Evaluation (WISE) Study to determine whether women with angiographic coronary artery disease (CAD) have elevated hostility and anger (e.g., in comparison to women without angiographic CAD). Logistic regression analysis revealed that of the anger and hostility measures, only Anger Out was a significant independent predictor of angiographic presence of CAD, with an OR of 1.08 (CI: 1.00-1.16) after controlling for significant risk factors. Hostility and anger scores were strongly related to baseline symptoms, with women who reported > 10 symptoms in their symptom history having significantly higher scores on all six measures of anger and hostility than women who reported <10 symptoms. These findings suggest that the outward expression of anger and hostility may be a CAD risk factor for women with suspected disease, and that higher levels of anger and hostility traits characterize highly symptomatic women.