Oxygen Consumption, Cerebral Oxygen Tension, and Cerebral Carbon Dioxide Tension During Ambient Hypoxia in Rhesus Monkeys.

摘要

Cerebral oxygen and carbon dioxide tensions as well as total oxygen consumption were monitored continuously in five conscious rhesus monkeys during exposure to ambient hypoxia. Ten experimental procedures on five monkeys demonstrated a linear relationship between ambient and cerebral oxygen tensions while oxygen consumption showed only a very slight dependence on ambient oxygen concentration. Cerebral carbon dioxide decreased slightly with hypoxia, and this decrease failed to be completely corrected with restoration of base line ambient and cerebral oxygen tensions. Thus, oxygen consumption was relatively constant during ambient hypoxia despite marked changes in cerebral oxygen tension as well as cerebral blood flow. (Author)