Integrated Device for Circulating Tumor Cell Capture, Characterization, and Lens-Free Microscopy.

摘要

For this project, we aim to develop and integrate two highly innovative new technologies to capture and characterize circulating tumor cells found in the blood of patients with breast cancer. The first is a highly innovative cell capture technology for blood and other body fluids based on a microfluidics microchip technology. The second is an entirely new imaging technology for performing wide field of viewing microscopy imaging. The resulting device will ultimately be clinically relevant, cost-effective, straight forward, and portable. It will address a significant technology deficiency in current circulating tumor cell analysis at the clinical level that is cost-effective and high-throughput.