Transplantation of Human Skull and Dura Mater

摘要

Over the past five years investigators at the Neuroskeletal Transplantation Laboratory, The Institute for Medical Research, San Jose, California, have studied the transplantation of human and animal skull and dura mater. Our goals have been the following: to understand the healing of fresh and preserved (frozen) autogenous human skull; to investigate the mechanisms by which autogenous and allogeneic canine skull becomes incorporated into host cranium; to modify allogeneic skull implants in order that repair be augmented; to develop an allogeneic malleable skull implant for universal use in human cranioplasty; to further the clinical application of allogeneic human bone, dura mater and fascia lata by providing a research base for progress in the transplantation of these tissues; to maintain a human tissue bank for clinical distribution of bone, dura mater and fasia lata; to participate in the formation of standards for the banking of human musculoskeletal tissue; to disseminate knowledge of tissue banking to neurosurgeons as primary providers and utilizers of transplantable tissue.