Decreased Free Fraction of Thyroid Hormones after Prolonged Antarctic Residence.

摘要

Humans who live in the polar regions of the globe are exposed to extremes of low temperatures, low relative humidity, increased electromagnetic radiation, changing photoperiods, and social isolation, Changes in physiology associated with prolonged circumpolar residence may increase our understanding of the reported human responses to midlatitude winters. Studies conducted in midlatitude regions suggest circannual or seasonal elevations in winter measurements of blood pressure and incidence of stroke and heart attack and increased frequency of mood disorder. Iodothyronines may alter cardiovascular function, lipid metabolism, and mood and adapt to conditions such as overfeeding, fasting, critical illness, and cold exposure.