Geographic Variation in Human Immunodeficiency Virus Seroconversion Rates in theU.S. Navy. (Reannouncement with New Availability Information)

摘要

The Navy population is centered around 19 U. S. home ports and several inlandduty stations. This is a study of variation in human immunodeficiency virus (HIV) seroconversions in Navy enlisted men by location in the United States, based on 949,570 enzyme-linked immunosorbent assays and 812 seroconversions during 1987-90. Seroconversion rates were higher in personnel in San Francisco (P=0.0004), Washington, DC (p=0.001), and Orlando, FL (p=0.04) than in other areas. They were lower in Charleston, SC, New London, CT, Seattle; and Brunswick, ME (p=<0.05). Black men had triple the seroconversion rate of all other men (p=<0.0001). After adjustment for race, age, marital status, and occupation, risk of seroconversion remained high in San Francisco (p=0.02) and Orlando (p=0.03). The risk of seroconversion in San Francisco was twice that of other areas in a cohort that did not change location (p=0.01). In contrast to declining trends overall in the Navy, rates did not decrease in Washington, DC, as a result consistent with previous calculations indicating a delayed second wave of HIV infection in the region. Geographic distribution, Human Immunodeficiency Virus (HIV), Acquired Immunodeficiency Syndrome (AIDS), Seroconversion rates.