Synthesis of New Benzoxaphosphole Derivatives from the Reaction of Dialkylphosphonates and Trisdialkylaminophosphines with 2,6-Bis(benzylidene)cyclohexanones

摘要

The reaction of 2,6-bis(benzylidene)cyclohexanones with dialkylphosphonates and tris(dialkylamino)phosphines afforded the new benzoxaphosphole derivatives (5a–5d) and (9a–9f). The biological activity of the newly synthesized compounds was also examined. Possible reaction mechanisms are considered, and the structural assignments are based on analytical and spectroscopic results. The structure of the new benzoxaphosphole 5a was confirmed by a single crystal X-ray determination.