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Adolescent synthetic cannabinoid exposures reported to texas poison centers

机译:向德克萨斯州毒物中心报告青少年合成大麻素暴露

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OBJECTIVE: This study describes the pattern of adolescent synthetic cannabinoid exposures reported to a large statewide poison center system. METHODS: Synthetic cannabinoid exposures among patients younger than 20 years reported to Texas poison centers during January 2010 to June 2011 were identified. The distribution of exposures by various demographic and clinical factors was determined. RESULTS: For 305 adolescent exposures, the mean age was 16.7 years (range, 12-19 y). The exposure was by inhalation in 77.4% of the cases, and 72.1% involved males. The exposure site was the patient's own residence in 70.5% of the cases, and a health care facility was the caller site in 68.9%. The patient was already at or en route to a health care facility in 80.3% of the cases, and the medical outcome was serious in 61.0%. The most frequently reported adverse clinical effects were tachycardia (41.6%), drowsiness/lethargy (24.3%), agitation/irritability (16.4%), vomiting (13.1%), hallucinations/delusions (11.5%), nausea (8.5%), confusion (8.2%), hypertension (7.5%), chest pain (6.9%), and dizziness/vertigo (5.2%). CONCLUSIONS: Adolescent synthetic cannabinoid exposures reported to Texas poison centers were more likely to involve inhalation. The adolescents were more likely to be male. The exposures more often occurred at the patient's own residence and managed at a health care facility with a serious outcome. This pattern of exposures was similar to that observed among adults.
机译:目的:本研究描述了报告给全州大型毒物中心系统的青少年合成大麻素暴露方式。方法:确定在2010年1月至2011年6月间向德克萨斯州毒物中心报告的20岁以下患者的合成大麻素暴露。确定了受各种人口和临床因素影响的暴露分布。结果:对于305名青少年暴露,平均年龄为16.7岁(范围12-19岁)。 77.4%的病例是通过吸入暴露的,男性为72.1%。在70.5%的病例中,暴露地点是患者自己的住所,在68.9%的病例中,医疗机构是呼叫者。在80.3%的病例中,患者已经在或正在前往医疗机构,而在61.0%的情况下,医疗结果很严重。最常见的不良临床反应是心动过速(41.6%),嗜睡/嗜睡(24.3%),躁动/烦躁(16.4%),呕吐(13.1%),幻觉/妄想(11.5%),恶心(8.5%),混乱(8.2%),高血压(7.5%),胸痛(6.9%)和头晕/眩晕(5.2%)。结论:向德克萨斯州毒物中心报告的青少年合成大麻素暴露更可能涉及吸入。青少年更有可能是男性。暴露更多地发生在患者自己的住所,并在医疗机构进行管理,结果很严重。这种暴露方式与成年人相似。

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