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Spontaneous Regression of a Congenital Melanocytic Nevus by Sclerosis

机译:先天性黑素细胞性硬化症的自发消退

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Congenital melanocytic nevi (CMNs) naturally evolve throughout life, growing proportionately with the child, darkening, and exhibiting textural or surface changes (e.g., papillomatous, verrucous, cerebriform), hypertrichosis, and, later in life, lightening of pigmentation. We report the case of a 5-year-old child with complete resolution of a medium sized CMN involving the distal left leg and foot via sclerosis and in the absence of any halo phenomenon. Spontaneous regression of CMN via sclerosis is rare, and it is thought that an immunologic mechanism different from the mechanism that the halo phenomenon induces mediates this regression. We reviewed the literature on this phenomenon and discuss how it might lead to regression of the nevus.
机译:先天性黑素细胞痣(CMN)终生自然进化,与孩子成比例增长,变黑并表现出质地或表面变化(例如乳头状,疣状,脑型),肥大性变态,以及生命后期色素沉着变浅。我们报告了一个5岁儿童的情况,该儿童完全硬化了一个中等大小的CMN,其中包括通过硬化的左腿和右腿远端,并且没有任何光晕现象。通过硬化而自发地CMN退行是罕见的,并且认为不同于晕轮现象诱导的机制的免疫机制介导了该退行。我们回顾了有关该现象的文献,并讨论了该现象如何导致痣消退。

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