Transformations of Alkyl 2-(2,2-Disubstituted-ethenyl)amino-3-dimethylaminoprop-2-enoates: Synthesis of Alkyl 3,4-Disubstituted- and Alkyl 1-Acyl-3,4-disubstituted Pyrrole-2-carboxylates

摘要

Alkyl 3,4-disubstituted pyrrole-2-carboxylates were obtained by cyclization of alkyl 2-(2,2-disubstituted-ethenyl)amino-3-(dimethylamino)prop-2-enoates in acidic media, while in the presence of acyl chlorides alkyl 1-acyl-3,4-disubstituted pyrrole-2-carboxylates were formed.