Synthesis of 2-aryloxyacetylamido-5-aryloxymethyl-1,3,4-thiadiazoles under solid-liquid phase transfer catalysis

摘要

2-Aryloxyacetylamido-5-aryloxymethyl-1,3,4-thiadiazoles 4_(1-15) are synthesized by the reaction of aryloxyacetic acids 1 with phenylsulfonyl chloride and 2-amino-5-aryloxymethyl-1,3,4-thiadiazoles 3 under solid-liquid phase transfer catalysis.