As the skin ages, the total lipid content in the skin decreases and proportion of skin lipids also changes, resulting in skin disorders caused by the diminished barrier function of the skin. Ceramide NS and butylene glycol can form a topical composition in which the ceramide NS is lamellar and can be used in topical applications for dry skin, skin irritation, skin wrinkles or other conditions in which the skin barrier is compromised, damaged, or disordered.
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