Cross-talk between LOX-1 and PCSK9 in vascular tissues

Ding Zufeng; Liu Shijie; Wang Xianwei; Deng Xiaoyan; Fan Yubo; Shahanawaz Jiwani; Reis Robert J. Shmookler; Varughese Kattayi I.; Sawamura Tatsuya; Mehta Jawahar L.

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Cross-talk between LOX-1 and PCSK9 in vascular tissues

机译：血管组织中LOX-1与PCSK9之间的串扰

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Aims Lectin-like ox-LDL receptor-1 (LOX-1) plays an important role in inflammatory diseases, such as atherosclerosis. Proprotein convertase subtilisin/kexin type 9 (PCSK9) modulates LDL receptor degradation and influences serum LDL levels. The present study was designed to investigate the possible interaction between PCSK9 and LOX-1.

机译：目的凝集素样ox-LDL受体1（LOX-1）在炎性疾病如动脉粥样硬化中起重要作用。前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型（PCSK9）调节LDL受体降解并影响血清LDL水平。本研究旨在研究PCSK9和LOX-1之间的可能相互作用。

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《Cardiovascular Research》 |2015年第4期|共12页
作者
Ding Zufeng; Liu Shijie; Wang Xianwei; Deng Xiaoyan; Fan Yubo; Shahanawaz Jiwani; Reis Robert J. Shmookler; Varughese Kattayi I.; Sawamura Tatsuya; Mehta Jawahar L.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
LOX-1; PCSK9; VCAM-1; Mitochondrial ROS;

机译：LOX-1;PCSK9;VCAM-1;线粒体ROS;

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1. Cross-talk between LOX-1 and PCSK9 in vascular tissues [J] . Ding Zufeng, Liu Shijie, Wang Xianwei, Cardiovascular Research . 2015,第4期

机译：血管组织中LOX-1与PCSK9之间的串扰
2. Cross-Talk Between PCSK9 and Damaged mtDNA in Vascular Smooth Muscle Cells: Role in Apoptosis [J] . Ding Zufeng, Liu Shijie, Wang Xianwei, Antioxidants and redox signalling . 2016,第18期

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3. Cross-Talk Between Adipose Tissue Health, Myocardial Metabolism and Vascular Function: The Adipose-Myocardial and Adipose-Vascular Axes [J] . Iozzo Patricia, Guzzardi Maria Angela Current pharmaceutical design . 2016,第1期

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6. Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX-1 in apoE-/- mice [O] . Li Yan, Qingling Jia, Hui Cao, 2021

机译：Fisetin通过调节PCSK9和Apoe - / - 小鼠的PCSK9和LOX-1改善动脉粥样硬化
7. P565Vascular endothelial cells exposed to oxidized HDL increases LOX-1 destination at the plasma membrane through a mechanism involving ROS/NOX/NF-kB/LOX-1 pathway [O] . F Simon, L Perez 2018

机译：暴露于氧化HDL的P565血管内皮细胞通过涉及ROS / NOx / NF-KB / LOX-1途径的机制增加了血浆膜的LOX-1目的地

Cross-talk between LOX-1 and PCSK9 in vascular tissues

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