Associations of serum C-reactive protein with physical activity, fitness and fatness in South African adolescents

摘要

Globally the prevalence of overweight is increasing significantly, not only in economically developed regions, but also in developing countries. In South Africa, the prevalence of combined overweight and obesity among high-school children increased from 21.2% in 2002' to 25% in 2008,2 with 35% of high-school girls being overweight or obese.The metabolic syndrome (MS) is a cluster of biological markers that together predict the development of cardiovascular disease and type 2 diabetes. These markers are hypertension, insulin resistance, central adiposity, hypertriglyceridaemia and decreased high-density lipoprotein cholesterol (HDL-C). The MS is now increasingly emerging among children and adolescents.3 Low-grade systemic inflammation is proposed as a significant component of the MS.