An increased pulsatility index in transcranial doppler sonography is associated with shiga-toxin-related encephalopathy in hemolytic uremic syndrome

摘要

Shiga-toxin (Stx)-producing Escherichia coli (STEC) causes hemorrhagic diarrhea and the potentially lethal hemolytic uremic syndrome (HUS) in severe cases. In 20-50% of the patients, HUS is complicated by involvement of the central nervous system (HUS-N) [1, 2]. Common neurological symptoms are seizures, alteration of consciousness, focal neurological deficits, visual disturbances and brainstem symptoms. Neurological manifestations are associated with increased morbidity and mortality.