Fabrication of CaSiO_3 bioceramics with open and unidirectional macro-channels using an ice/fiber-templated method

摘要

Porous CaSiO_3 bioceramics with open and unidirectional macro-channels of pore size more than 200 μm are of particular interest for biomedical applications. An ice/fiber-templated method was employed for the fabrication of CaSiO_3 bioceramics with interconnected lamellar pores and macro-channels of pore size more than 200 μm. The pores formed by ice crystals transformed from cellular to lamellar, while the pores formed by fibers were aligned macro-channels, which were also in alignment with the lamellar pores. Keeping the initial slurry concentration constant and increasing the packing density of fibers, the volume fraction of macro-channels and open porosity increased, and the compressive strength decreased. Maintaining the packing density of fibers and increasing the initial slurry concentration, the pore sizes of lamellar pores and open porosity decreased, and the compressive strength increased. The results indicated that it was possible to manufacture porous CaSiO_3 bioceramics with the macro-channels of 250-350μm, lamellae spacing of 50-100 μm, open porosity of 71.12-83.94% and compressive strength of 0.87-3.59 MPa, indicating the suitability for tissue engineering.