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Comparison of Interscalene Brachial Plexus Block Performed With and Without Steroids

机译:有无类固醇激素的肌间沟臂丛神经阻滞的比较

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摘要

This prospective comparative clinical study was performed to evaluate the effect of triamcinolone when added to bupivacaine during brachial plexus blockade in patients undergoing shoulder surgery. Interscalene brachial plexus blocks were performed on 910 patients before shoulder surgery. Of the patients, 574 were randomly allocated to receive steroids added to the injected local anesthetic and 336 patients received local anesthetic without steroids. All patients were followed prospectively to evaluate the rate of successful anesthesia, duration of anesthesia, side effects of the block, adverse events, and persistent neurologic complications associated with interscalene brachial plexus block. Patients who received steroids had statistically longer pain relief than those who did not receive steroids (P<.001). No difference was found in adverse events, complications, or side effects. Compared with blocks performed without steroids, a statistically longer duration of block analgesia occurred with the addition of steroids to the local anesthetic solution during brachial plexus blockade. Rates of side effects, adverse events, and persistent neurologic complications were similar between the groups.
机译:这项前瞻性比较临床研究旨在评估在接受肩部手术的患者臂丛神经阻滞期间将曲安西龙添加到布比卡因中的效果。 910例患者在肩部手术前进行了斜肌间臂丛神经阻滞。在这些患者中,随机分配了574名患者接受注射类固醇的类固醇激素治疗,有336名患者接受了无类固醇的局部麻醉剂治疗。所有患者均接受前瞻性随访,以评估成功麻醉的速度,麻醉的持续时间,阻滞的副作用,不良事件以及与斜肌间臂丛神经阻滞相关的持续性神经系统并发症。据统计,接受类固醇治疗的患者比未接受类固醇治疗的患者具有更长的疼痛缓解时间(P <.001)。不良事件,并发症或副作用没有发现差异。与不使用类固醇进行的阻滞相比,在臂丛神经阻滞期间向局部麻醉溶液中添加类固醇会产生统计学上更长的阻滞镇痛时间。两组之间的副作用,不良事件和持续的神经系统并发症发生率相似。

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