Axially Chiral NHC-Pd(II) Complexes in the Oxidative Kinetic Resolution of Secondary Alcohols Using Molecular Oxygen as a Terminal Oxidant

摘要

Axially chiral N-heterocyclic carbene (NHC) Pd(II) complexes were prepared from optically active 1,1'-binaphthalenyl-2,2'-diamine (BINAM) and H_8-BINAM and applied in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant. The corresponding sec-alcohols can be obtained in good yields with moderate to good enantioselectivities.