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Genome biology: Not drowning but waving

机译:基因组生物学:不是淹没而是挥手

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One could be forgiven for thinking that biology is in turmoil following recent discoveries that seem to undermine conventional wisdom surrounding the role of genomes in evolution (Ball, 2013). Is the vast excess of genomic DNA—hitherto dismissed as junk—indispensable after all? Are the effects of the environment often transmitted between generations regardless of the information in genes? What is a gene these days anyway? Such speculations are exhilarating, but I suggest that most biologists are not more confused than ever about the role of genes in evolution but, rather, less. Yes, "the very definition of a gene is hotly debated" (Ball, 2013), but no more than it ever was. The perennial student essay topic, "What is a gene?", has become hackneyed through overuse. And the answer to the question is, as ever, "it depends." Leaving the definition flexible has not discernibly hindered the remarkable progress of genetics. Of course, one can never discount the possibility that a scientific revolution will sweep away current perceptions, but this will require a level of scientific rigor that much of the apparently conflicting data currently lacks.
机译:有人认为最近的发现似乎破坏了围绕基因组在进化中的作用的传统观念,生物学就处于动荡之中,这是可以原谅的(Ball,2013)。毕竟,基因组DNA的大量过量(至今被视为垃圾)是必不可少的吗?不管基因信息如何,环境的影响是否经常在世代之间传播?这些天到底是什么基因?这种猜测令人振奋,但我建议大多数生物学家对基因在进化中的作用的了解比以往任何时候都更加混乱,而更少。是的,“基因的确切定义引起了激烈的争论”(Ball,2013年),但没有比以往任何时候都多的了。多年生的学生论文题目“什么是基因?”由于过度使用而变得刻板。这个问题的答案和以往一样是“取决于情况”。保持定义的灵活性并没有明显地阻碍遗传学的显着进步。当然,人们永远无法轻视一次科学革命将席卷当前观念的可能性,但这将需要一定程度的科学严谨性,而目前缺乏许多明显矛盾的数据。

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