Five-Membered 2,3-Dioxo Heterocycles: LXXXV. Synthesis of Methyl 1-Aryl-4,5-dioxo-3-(1-oxo-3-phenylprop-2-en-1-yl)-4,5-dihydro-1H-pyrrole-2-carboxylates and Their Reaction with 3-Amino-5,5-dimethylcyclohex-2-en-1-ones. Molecular and Crystalline Structure of 4'-Hydroxy-1'-(4-methoxyphenyl)-6,6-dimethyl-3'-(1-oxo-3-phenylprop-2-en-1-yl)-1-phenyl-6,7-dihydrospiro[indole-3,2'-pyrrole]-2,4,5'(1H,1'H,5H)-trione

摘要

Treatment of methyl 2-arylamino-4-oxo-6-phenylhexa-2,5-dienoates with oxalyl chloride gave methyl 1-aryl-4,5-dioxo-3-(1-oxo-3-phenylprop-2-en-]-yl)-4,5-dihydro-1H-pyrrole-2-carboxylates which reacted with 3-benzylamino- and 3-arylamino-5,5-dimethylcyclohex-2-en-1-ones to produce 1'-aryl-1-benzyl- and 1,1'-diaryl-4'-hydroxy-6,6-dimethyl-3'-(1-oxo-3-phenylprop-2-en-1-yl)-6,7-dihydrospiro[indole-3,2'-pyrrole]-2,4,5'( 1H, 1'H,5H)-triones.