The risk of uterine malignancy is linearly associated with body mass index in a cohort of US women

摘要

The aim of this retrospective study was to quantify the relationship of uterine cancer with body mass index (BMI) in a cohort of US women undergoing hysterectomy. The authors used the University Health System Consortium database to identify all women who underwent total hysterectomy between 2008 and 2012 with a recorded BMI of 25 to 40 kg/m2. A total of 165,876 women were identified. Least squares regression analysis was used to assess the association between increasing BMI and the proportion of women with a diagnosis of uterine cancer. Adjustment for other known risk factors (including age, race, and other comorbidities) was performed using multivariate binary logistic regression.