Synthesis of Fused Indolizine Derivatives (Pyrrolo[l,2-a]quinolines) by Annulation of 2-Methyl-l-pyrrolidine with 2-Acylcyclohexane-l,3-diones

摘要

Annulation of cyclic Schiff bases (3,4-dihydroiso-quinolines,4,9-dihydro-3H-beta-carbolines,etc) with beta-di- and p,p'-tricarbonyl compounds (p-diketones,p-keto esters,2-acylcyclane-l,3-diones,and 3-acyl derivatives of tetramic,tetronic,and thiotetronic acids,etc.) has assumed increasing importance in the design of molecular skeletons of fused nitrogenous hetero-cycles with an angular nitrogen atom [1-4].