Organylthiochloroacetylenes: III.~1 Nucleophilic Addition of Di(2-phenylethyl) phosphine Oxide to Alkylthiochloroacetylenes: Configuration and Conformation of Adducts

摘要

Alkylthiochloroacetylenes regio- and stereospecifically react with di(2-phenylethyl) phosphine oxide in dioxane at 20-22 deg C in the presence of potassium hydroxide to form 1-chloro-2-(alkylthio) vinyl [di(2-phenylethyl)] phosphine oxides in a 78-85% yield. According to IR and ~1H and ~(31)P NMR data, dielectrometric measurements, and quantum-chemical calculations, the obtained adducts have the Z configuration and exist mainly in the sp, sp conformation.