Synthesis of maleate derivatives in isocyanide-base MCRs: reaction of 2-mercaptobenzoxazole with alkyl isocyanides and dialkyl acetylenedicarboxylates

摘要

Dialkyl 2-((alkylimino)(2-thioxobenzo[d]oxazol-3(2H)-yl)methyl) maleate derivatives were obtained from the reaction between alkyl isocyanides, dialkyl acetylene dicarboxylates, and 2-mercaptobenzoxazole in CH2Cl2 at room temperature in good yields.