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首页> 外文期刊>Neurological Research: An Interdisciplinary Quarterly Journal >The management of malignant spinal cord compression: A modified technique of spinal reconstruction
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The management of malignant spinal cord compression: A modified technique of spinal reconstruction

机译:恶性脊髓压迫的处理:改良的脊柱重建技术

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Objectives: This study aims to assess the results of a single-stage posterolateral transpedicular corpectomy and fusion in malignant spinal cord compression of the thoracolumbar spine. Methods: Sixteen cases of thoracolumbar metastases were treated with single-stage posterolateral transpedicular corpectomy and fusion. A modified technique of nerve preserving bilateral cage placement was described. Pain, American Spinal Injury Association (ASIA) scores, spinal deformity, primary pathologies, and survival were recorded. Results: The most common primary pathology was lung, followed by renal and colorectal cancer. Significant pain reduction was achieved in all patients, regardless of previous nonsurgical treatment. No patient suffered neurological deterioration after surgery. For the 10 patients who presented with neurological deficits, 90% improved after surgery. Significant improvement in Cobb angle and vertebral height were observed postoperatively. A mean survival of 5.6 months was recorded at the completion of this manuscript. Discussion: Single-stage posterolateral transpedicular corpectomy and fusion appeared to be a safe and an effective approach in malignant spinal cord compression. The current modified technique extends its application to lumbar spine by preserving all nerve roots. The significant improvement of pain and neurological deficits leads to better quality of life. The benefits of surgery in the overall survival remain to be investigated.
机译:目的:本研究旨在评估胸腰椎恶性脊髓压迫的单阶段后外侧经蒂椎弓根切除术和融合的结果。方法:对16例胸腰段转移瘤进行单期后外侧经蒂椎弓根切除并融合治疗。描述了一种改良的保留双侧笼神经的技术。记录疼痛,美国脊柱损伤协会(ASIA)的评分,脊柱畸形,主要病理和生存情况。结果:最常见的主要病理是肺癌,其次是肾癌和大肠癌。无论以前是否接受非手术治疗,所有患者的疼痛均明显减轻。术后无患者神经功能恶化。对于出现神经功能缺损的10例患者,手术后90%改善。术后观察到Cobb角和椎高明显改善。在完成该手稿时,平均生存期为5.6个月。讨论:单期后外侧经蒂椎弓根切除和融合似乎是恶性脊髓压迫的安全有效方法。通过保留所有神经根,当前改进的技术将其应用扩展到腰椎。疼痛和神经功能缺损的明显改善可改善生活质量。手术对整体生存的益处尚待研究。

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