A chemoselective and one-pot synthesis of 5-hydroxy and 7-hydroxy coumarin derivatives

摘要

An efficient one-pot reaction of dialkyl acety-lenedicarboxylates with 2,4-dihydroxybenzo(or aceto) phenones in the presence of triphenylphosphine produces 5-hydroxy- and 7-hydroxycoumarin derivatives. The novel procedure features short reaction time, fairly good yields, and simple workup.