Fused azolium salts XVIII. Synthesis and reactivity of a novel fused heteroaromatic system: [1,2,3]Triazolo[l,5-b]isoquinolinium salts

摘要

Oxidative cyclization of 3-isoquinolyl ketone hydrazones afforded the novel tricyclic heteroaromatic [1,2,3]triazolo[1,5-b]isoquinolinium salts. The reactivity of the ring system towards nucleophiles proved to be regioselective. Secondary amines induced ring opening of the pyridine moiety, forming a triazolyl substituted benzaldehyde derivative; sodium borohydride afforded partially reduced derivatives of the parent compound. [References: 11]