Prostate cancer: Defining biochemical failure in patients treated with HIFU

摘要

No established definition exists of therapeutic success after high-intensity focused ultrasound in patients with localized prostate cancer. A recent analysis has proposed a definition of biochemical failure for use in this setting. However, much work still needs to be done on identifying suitable predictors of clinical failure, and large-scale validation is certainly required. High-intensity focused ultrasound (HIFU) is a minimally invasive therapy that is increasingly used in management of localized prostate cancer that recurs after primary treatment. HIFU waves delivered via contiguous targeted shots are used to treat the entire prostate gland, inducing a coagulation necrosis