Is carotid angioplasty followed by cardiac surgery a safe and effective treatment for carotid artery stenosis?

摘要

This was a prospective, observational study of consecutive patients scheduled to undergo CAS and cardiac surgery between December 1997 and June 2005 at St Antonius Hospital, Nieuwegein, The Netherlands. All participants had an indication for cardiac surgery (i.e. coronary artery disease with myocardial ischemia, dissection or aneurysm of the ascending aorta or aortic arch, or symptomatic valve disease) and severe (>80%) carotid stenosis, and none had experienced an ipsilateral cerebrovascular event in the 4 months preceding enrollment. Patients were excluded if they had severe diffuse atherosclerosis, peripheral vascular disease that prevented femoral catheterization, severe renal impairment (serum creatinine >300 mumol/l), or a major neurological deficiency.