Not all shifts are equal: it's time for comprehensive exposure metrics in chronodisruption research.

摘要

In a prospective Nurses' Health Study of a subset of 53,487 women, Viswanathan and colleagues, found a 2-fold increase in endometrial cancer risk among obese females working rotating night shifts (1). Whereas the authors acknowledge that their findings require confirmation, this would constitute a novel end point associated with long-term nightwork beyond breast cancer. A press release that accompanied IARC's recent classification "shift-work that involves circadian disruption is probably carcinogenic to humans" (Group 2A; ref. 2), asked exactly for that: ".. .more studies are needed to examine the potential riskin other professions and for other cancers" beta).