Free-radical addition of phosphine sulfides to aryl and hetaryl acetylenes: unprecedented stereoselectivity

摘要

Secondary phosphine sulfides react stereo- and regioselectively with aryl and hetaryl acetylenes in the presence of radical initiators (AIBN, 60-65 ℃) in the anti-Markovnikov mode giving Z-isomers of the corresponding monoadducts in high yields.