Kawasaki disease was first described in 1967 by the Japanese paediatrician Tomisaku Kawasaki. In 80%, cases affected children are aged less than five years. Older children are only rarely affected [1]. Clinically Kawasaki disease is an acute onset illness characterized by high fever with mucocutaneous changes and lymphadenitis. Fever is a constant feature in Kawasaki disease and usually ranges between 38-40癈 with irregular spikes. Mucocutaneous changes are seen in 90% cases. The five principal criteria along with fever of five days duration for diagnosis of Kawasaki disease are (i) bilateral bulbar non exudative conjunctivitis (ii) changes of mucosa of oropharynx including dry fissured lips, injected pharynx, strawberry tongue (iii) changes of the peripheral extremities such as edema or erythema of hands and feet, desquamation usually beginning periungually (iv) rash which is non vesicular and primarily truncal (v) cervical lymphadenopathy [2]. Other associated features of Kawasaki disease are arthritis, irritability, aseptic meningitis, urethritis and diarrhea.
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