Antioxidant and Antiproliferative Activities of Loach (Misgumus anguillicaudatus) Peptides Prepared by Papain Digestion

摘要

Loach protein hydrolysates (LPH) prepared by papain digestion were fractionated into four fractions, LPH-I (MW > 10 kDa), LPH-II (MW = 5-10 kDa), LPH-III (MW = 3-5 kDa), LPH-IV (MW 0.05), with significantly less growth than those of LPH-L LPH-II, and LPH-III, respectively (p 0.86, p < 0.01) with the antiproliferative activity of the three cancer cell lines, suggesting that higher antioxidant activity leads to better antiproliferative activity. However, further mechanistic and human clinical studies of the anticancer activity of loach protein hydrolysate fractions are needed.