Trial finds adding amlodipine to benazepril reduces diastolic blood pressure in non-responders to benazepril monotherapy

摘要

In the United States, only one third of people with hypertension have blood pressure controlled as recommended by national guidelines. People with hypertension often need two or more medications to achieve blood pressure targets. Chrysant and colleagues compared the efficacy and safety of adding amlodipine besylate to benazepril hydrochloride for people whose hypertension was not controlled with benazepril alone. The primary endpoint was change in mean sitting diastolic blood pressure from baseline.