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Genetics and attribution issues that confront the microbial forensics field.

机译:微生物法医学领域面临的遗传和归因问题。

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摘要

The commission of an act of bioterrorism or biocrime is a real concern for law enforcement and society. Efforts are underway to develop a strong microbial forensic program to assist in identifying perpetrators of acts of bioterrorism and biocrimes, as well as serve as a deterrent for those who might commit such illicit acts. Genetic analyses of microbial organisms will likely be a powerful tool for attribution of criminal acts. There are some similarities to forensic human DNA analysis practices, such as: molecular biology technology, use of population databases, qualitative conclusions of test results, and the application of QA/QC practices. Differences include: database size and composition, statistical interpretation methods, and confidence/uncertainty in the outcome of an interpretation.
机译:实施生物恐怖主义或生物犯罪行为是执法和社会的真正关注。目前正在努力制定强有力的微生物法医方案,以协助查明生物恐怖主义和生物犯罪行为的肇事者,并对那些可能犯下这种非法行为的人起到威慑作用。微生物的遗传分析可能会成为犯罪行为归因的有力工具。法医人类DNA分析方法有一些相似之处,例如:分子生物学技术,种群数据库的使用,测试结果的定性结论以及QA / QC方法的应用。差异包括:数据库大小和组成,统计解释方法以及解释结果的置信度/不确定性。

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