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Exclusions and attributions of paternity: practical experiences of forensic genetics and statistics.

机译:父权的排除和归因:法医遗传学和统计学的实践经验。

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摘要

The Swedish State Institute for Blood Group Serology is a central government laboratory handling all blood typing in paternity cases in Sweden, each year testing 1,500-2,000 cases using about 13 polymorphisms. Of the accused men, 35%-40% are nonfathers, but in one-man cases (about 78% of all cases), approximately 75% are the true fathers. Exclusions appear to be distributed as expected from allele frequencies, and the paternity probability of nonexcluded men is assessed with a Bayesian approach. Some cases are retested in extended investigations which raise theoretical exclusion capability from about 87% to about 99%. Both the results of extended investigations and the theoretical consideration of the distribution of paternity probabilities support the use of such positive statistical evidence for the attribution of paternity.
机译:瑞典国家血液小组血清学研究所是中央政府的实验室,负责处理瑞典陪产假病例中的所有血型,每年使用约13种多态性检测1,500-2,000例病例。在被告中,有35%-40%是非父亲,但在单人案件中(约占所有案件的78%),约有75%是真正的父亲。从等位基因频率看来,排除情况似乎是预期的分布,并且未排除男性的父子关系概率通过贝叶斯方法进行评估。在扩展的研究中对一些案例进行了重新测试,从而将理论排除能力从大约87%提高到了大约99%。扩展调查的结果以及对父系概率分布的理论考虑都支持将此类积极的统计证据用于父系归因。

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