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Comparative study of the reconstruction of articular cartilage defects with free costal perichondrial grafts and free tibial periosteal grafts: an experimental study on rabbits.

机译:游离肋骨软骨膜移植物和游离胫骨骨膜移植物重建关节软骨缺损的比较研究:对兔的实验研究。

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The purpose of this study was to compare the chondrogenic potential of free perichondrial with free periosteal grafts in the resurfacing of full-thickness defects of patellar articular cartilage in rabbits. We used adolescent New Zealand rabbits weighing between 2.4 and 3.6 kg. A 6-mm wide and 3-mm thick defect was created on the patellar articular surface. A total of 30 rabbits were randomly divided into a control group and two test groups. One test group received free perichondrial grafts (PC); the other received free periosteal grafts (PO). All the animals were killed 8 weeks after surgery. All the histological samples were scored from 0 to 17 according to a standard scoring system. Differences in the quality of the regenerated tissue were only found between the control and the test groups. There were no statistically significant histological differences between the grafted defects of the PC and the PO groups that there are not on any of the variables. The results of this study support that there are not significant differences in the quality of the repair tissue when using these two types of biological grafts.
机译:本研究的目的是比较游离软骨膜和游离骨膜移植物在重建in骨关节软骨全层缺损中的软骨形成潜力。我们使用了体重在2.4至3.6千克之间的青春期新西兰兔。 the骨关节表面形成了6毫米宽和3毫米厚的缺损。将总共​​30只兔随机分为对照组和两个测试组。一个测试组接受了免费的软骨膜移植物(PC)。另一个接受了游离的骨膜移植(PO)。手术后8周将所有动物杀死。根据标准评分系统,所有组织学样本均从0到17进行评分。仅在对照组和测试组之间发现了再生组织质量的差异。 PC和PO组的移植缺损之间在统计学上没有明显的组织学差异,没有任何变量。这项研究的结果支持当使用这两种类型的生物移植物时,修复组织的质量没有显着差异。

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