Concise Synthesis of Biologically Interesting (+-)-Cannabichromene,(+-)-Cannabichromenic Acid,and (+-)-Daurichromenic Acid

摘要

Total synthesis of biologically interesting (+-)-cannabichromene,(+-)-cannabichromenic acid,and (+-)-daurichromenic acid is described.The key step in the synthetic strategy involves the formation of benzopyrans by ethylenediamine diacetate-catalyzed reactions of resorcinols with alpha,beta-unsaturated aldehydes.