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Surgical treatment for aortic periannular abscess/pseudoaneurysm caused by infective endocarditis

机译:感染性心内膜炎引起的主动脉瓣环周围脓肿/假性动脉瘤的手术治疗

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Delayed diagnosis or surgery sometimes causes more extensive destruction of aortic periannular abscess, or pseudoaneurysm, resulting in left ventricular-aortic discontinuity, particularly in patients with prosthetic valve endocarditis. The condition complicates the surgical procedures and causes worsening of short- and long-term outcomes. In-hospital mortality in patients with prosthetic valve endocarditis has been reported to be as high as 15-20 %, even at leading hospitals in the world. Contemporary modes of surgery for periannular abscess/pseudoaneurysm involve drainage of the cavity, radical debridement of necrotic tissue, annular reconstruction of the destroyed annulus, and root replacement using an optimal conduit. Radical debridement is of primary importance and is the universally accepted procedure, which frequently requires annular reconstruction using a pericardial patch. Conventional aortic valve replacement using a mechanical or stented biological valve, aortic valve replacement with translocation, aortic root replacement using an allograft, pulmonary autograft (Ross procedure), stentless biological valve, or a composite graft are conduits of choice. All things considered, allograft is believed to be the best conduit for a destroyed annulus because of better fit and its resistance to infection; however, recent reports have failed to confirm the superiority of allograft over other conduits in terms of long-term survival and freedom from reoperation/recurrence of infection. Short- and long-term outcomes have been studies for every type of conduit, but the selection of conduits for aortic root replacement is still controversial.
机译:延迟的诊断或手术有时会导致主动脉瓣环周围脓肿或假性动脉瘤的更广泛破坏,从而导致左心室主动脉间断,尤其是在人工瓣膜心内膜炎的患者中。该病使手术过程变得复杂,并导致短期和长期预后恶化。据报道,即使在世界领先的医院中,人工瓣膜性心内膜炎患者的院内死亡率也高达15-20%。瓣膜周围脓肿/假性动脉瘤的现代外科手术方式包括腔腔引流,坏死组织的根治性清除,环形环的破坏以及使用最佳导管的牙根置换。根治性清创术是最重要的,并且是普遍接受的手术,通常需要使用心包膜片进行环形重建。使用机械或带支架生物瓣膜的常规主动脉瓣置换,带移位的主动脉瓣置换,使用同种异体移植,肺自体移植(Ross手术),无支架生物瓣膜或复合移植物替代主动脉根部是首选导管。考虑到所有因素,同种异体移植物因具有更好的适应性和抗感染性而被认为是破坏环面的最佳导管。然而,最近的报道未能证实同种异体移植在长期存活和无再次手术/感染复发方面优于其他导管。已经针对每种类型的导管进行了短期和长期结果的研究,但是主动脉根置换的导管选择仍存在争议。

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