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首页> 外文期刊>European journal of clinical investigation >Upregulated thymic stromal lymphopoietin receptor expression in children with asthma
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Upregulated thymic stromal lymphopoietin receptor expression in children with asthma

机译:哮喘儿童胸腺基质淋巴细胞生成素受体表达上调

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摘要

Background Thymic stromal lymphopoietin (TSLP) plays an important role in pathogenesis in patients with asthma. However, the role of thymic stromal lymphopoietin receptor (TSLPR) and correlation with IL-7R alpha and clinical severity in asthmatic or nonasthmatic children remain unclear. We investigated TSLPR and IL-7R alpha mRNA levels in asthma and nonasthma and assessed TSLPR expression in children who were sensitive to mites.
机译:背景胸腺基质淋巴细胞生成素(TSLP)在哮喘患者的发病机理中起着重要作用。然而,哮喘或非哮喘儿童的胸腺基质淋巴细胞生成素受体(TSLPR)的作用以及与IL-7Rα的相关性和临床严重性仍不清楚。我们调查了哮喘和非哮喘病中TSLPR和IL-7RαmRNA的水平,并评估了对螨虫敏感的儿童的TSLPR表达。

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