Targeting the IVD clock to halt degeneration

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Targeting the IVD clock to halt degeneration

机译：靶向 IVD 时钟以阻止退化

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New research sheds light on how disruption of peripheral circadian rhythms mediates inflammation-induced intervertebral disc degeneration and suggests a therapeutic approach to target these mechanisms.

机译：新的研究揭示了外周昼夜节律的破坏如何介导炎症诱导的椎间盘退行性变，并提出了一种针对这些机制的治疗方法。

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《Nature reviews. Rheumatology》 |2022年第10期|553-553|共1页
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SarahOnuora;
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Nature Reviews Rheumatology;

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正文语种英语
中图分类内分泌腺疾病及代谢病;
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1. TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice [J] . Mitchel C.Whittal, Sarah J.Poynter, KaylaSammsK. JoshBriarSabrina I.SinopoliMagaliMillecampsLaura S.StoneStephanie J.DeWitte-OrrDiane E.Gregory European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society . 2022,第10期

机译：TAK-242 treatment and its effect on mechanical properties and gene expression associated with IVD degeneration in SPARC-null mice
2. The Role of Circadian Clock Genes in Critical Illness: The Potential Role of Translational Clock Gene Therapies for Targeting Inflammation, Mitochondrial Function, and Muscle Mass in Intensive Care [J] . Poole Joanna, Ray David Journal of biological rhythms . 2022,第4期

机译：The Role of Circadian Clock Genes in Critical Illness: The Potential Role of Translational Clock Gene Therapies for Targeting Inflammation, Mitochondrial Function, and Muscle Mass in Intensive Care
3. Getting the clock back on its feet: targeting the circadian clock to treat osteoarthritis [J] . Thomas Mortimer The FEBS journal. . 2022,第21期

机译：Getting the clock back on its feet: targeting the circadian clock to treat osteoarthritis
4. Correlating HALT HASS, RS/HALT Vibration and End-Use Environments [C] . Stephen A. Smithson Annual technical meeting of the Institute of Environmental Sciences and Technology . 2015

机译：关联HALT和HASS，RS / HALT振动和最终使用环境
5. Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2 [D] . Yu, Qinhong. 2019

机译：Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2
6. The IVD Directive and Availability of Reference Systems for IVD Medical Devices: A View from Industry [O] . Neil Greenberg 2001

机译：IVD指令的IVD指令和参考系统的可用性：行业观点
7. Identification of a target protein of Hydra actinoporin-like toxin-1 (HALT-1) using GST affinity purification and SILAC-based quantitative proteomics [O] . Hong Xi Sha, Jung Shan Hwang 2017

机译：使用GST亲和纯化和基于氧化基于氧化硅酸溶素样毒素-1（HALT-1）的Hydra Actinoporin毒素-1（Halt-1）的靶蛋白
8. Revised Recovery Plan for Macfarlane's Four-O'Clock ('Mirabilis macfarlanei'). [R] . 2000

机译：macfarlane的Four-O'Clock（'mirabilis macfarlanei'）的修订恢复计划。

Targeting the IVD clock to halt degeneration

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