A MAJORITY OF PARENTS ACCEPT NEWBORN SCREENING FOR FRAGILE X Prospect of mandatory state screening still an area ofdebate

摘要

The most common cause of inherited intellectual disabilities, FXS is an X-linked condition caused by a CGG expansion of more than 200 repeats in the FMR1 gene. Those repeats lead to reduction or absence of FMRP, a protein necessary for normal brain development and functioning. The result is a spectrum of psychological, neurological, and behavioral problems, including autism, anxiety, hyperactivity, and inattention.