Sickle Cell Disease: Screening, Diagnosis, Management, and Counseling in Newborns and Infants. Clinical Practice Guideline Number 6; Sickle Cell Disease: Comprehensive Screening and Management in Newborns and Infants. Quick Reference Guide for Clinicians Number 6; Sickle Cell Disease in Newborns and Infants. A Guide for Parents

摘要

The clinical practice guideline sets forth a comprehensive program for identifying, diagnosing, and treating newborns and infants with sickle cell disease and recommends education and counseling strategies for their parents. Sickle cell disease is a term for a group of genetic disorders characterized by production of hemoglobin S(Hb S), anemia, and acute and chronic tissue damage secondary to the blockage of blood flow produced by abnormally shaped red blood cells. Sickle cell anemia is the most common form of the disease and is estimated to affect more than 50,000 Americans. A clinical practice guideline and quick reference guide provide background information and recommendations for clinicians, and a parent's guide explains sickle cell disease, usual treatments and complications, and the signs and symptoms which indicate that a child with sickle cell disease needs immediate medical attention; the parent's guide also includes a list of resources for further information.