Independent role of high central venous pressure in predicting worsening of renal function in chronic heart failure outpatients

摘要

In heart failure (HF) patients, an impairment of the renal function, as well as a worsening of this condition, is frequently observed and both have been demonstrated to be independently associated with a greater morbidity and mortality [1,2]. Over the last years, the role of an increased central venous pressure (CVP) during acute decompensated heart failure (ADHF) in determining worsening renal function (WRF) has been well defined [3], but only few data about its role in chronic patients are available [4]. We sought to better define the predictors of a worsening renal function in a group of outpatients affected by chronic HF (CHF) in stable clinical conditions, focusing on non-invasive parameters reflecting right ventricular pressure.