Lipid Metabolic Alterations andSatiety with a Pumpkin-Based supplementin Obese Dogs

摘要

To evaluate the combined effects of a dietary fiber and carnitine supplement using a commercially available canned dog supplement on satiety, weight loss, and lipid metabolism.Design-A randomized, crossover design (satiety study) and randomized complete block design (weight loss study) Sample Population-12 (satiety study) and 7 (weight loss study) adult female overweight/ obese Beagles.Procedures-Two studies were conducted. In the satiety study, dogs were fed 1.2 times maintenance energy amounts of either high dietary fiber/high carnitine (HF/C) or lowdietary fiber/low carnitine (LF/C) supplemented diet twice a day using a 3 hour interval and food intake was monitored. Blood samples were obtained at 0, 45, and 120 min postprandially for peptide YY determination. For the weight loss study, 60 % of maintenance energy amounts of either the HF/C or LF/C diet were fed for 42 days. Blood samples were collected at days 1, 28, and 42 to determine plasma lipid metabolites and peptide YY.