CARDIAC FUNCTION AND METABOLIC PARAMETERS IN OBESE DOGS

摘要

In people, obesity is an independent risk factor for the development of obesity related cardiac dysfunction (ORCD) characterized by systolic dysfunction, diastolic dysfunction, and/or vascular endothelial dysfunction. Components of metabolic syndromeincluding dyslipidemias, elevated inflammatory markers, and insulin resistance are believed to play an important role in the pathophysiology of ORCD. Obesity is reaching epidemic proportions in dogs and it is estimated that approximately 34% of dogs areoverweight and 5% are obese in the United States. Recent studies performed in dogs suggest that metabolic syndrome also exists in obese dogs, warranting further investigation into the risk for ORCD.