Vibriocidal activity of certain medicinal plants used in Indian folklore medicine by tribals of Mahakoshal region of centralIndia

摘要

Objectives: Screening of the medicinal plants and determination of minimum inhibitoryconcentration (MIC) against Vibrio cho/erae and Vibrio parahaemolyticus.Materials and Methods: A simple in vitro screening assay was employed for thestandard strain of Vibrio cho/erae, 12 isolates of Vibrio cholerae non-O1, and Vibrioparahaemolyticus. Aqueous and organic solvent extracts of different parts of the plantswere investigated by using the disk diffusion method. Extracts from 16 medicinal plantswere selected on account of the reported traditional uses for the treatment of cholera andgastrointestinal diseases, and they were assayed for vibriocidal activities.Results: The different extracts differed significantly in their vibriocidal properties withrespect to different solvents. The MIC values of the plant extracts against test bacteriawere found to be in the range of 2.5-20 mg/ml.