首页> 外文期刊>Indian Journal of Chemistry, Section B. Organic Including Medicinal >synthesis of novel 2-(5'-substituted-2'-phenylindole-3'-yl)-5-(coumarin-3'-yl)-1,3,4-oxadiazoles and 4-(5'-substituted-2'-phenylindole-3'-yl)-1-(coumarin-3'-amido)azetidin-2-one and their antimicrobial activity.
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synthesis of novel 2-(5'-substituted-2'-phenylindole-3'-yl)-5-(coumarin-3'-yl)-1,3,4-oxadiazoles and 4-(5'-substituted-2'-phenylindole-3'-yl)-1-(coumarin-3'-amido)azetidin-2-one and their antimicrobial activity.

机译:新型2-(5'-取代-2'-苯基吲哚-3'-基)-5-(香豆素-3“-基)-1,3,4-恶二唑和4-(5'-取代-2 '-苯基吲哚-3'-基)-1-(香豆素-3“-氨基)氮杂环丁烷-2-酮及其抗菌活性。

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摘要

5-Substituted-2-Phenylindol-3-carboxaldehydes 1a-c are reacted withcoumarin-3-hydrazide 2 to get coumarin-(5'-subsittuted-2'-phenylindole-3'-carboxaldehyde)-3-carbonylhydrazone 3a-c.Compounds 3a-c on oxidation with FeCl_3 yield 2-(5'-substituted-2'-phenylindole-3'-yl)-1-(coumarin-3"-amido)azetidin-2-ones 5a-c.All thesynthesized compounds have been screened for their antimicrobial activity.
机译:使5-取代的2-苯基吲哚-3-羧醛1a-c与香豆素-3-酰肼2反应,得到香豆素-(5'-亚取代的2'-苯基吲哚-3'-甲醛)-3-羰基hydr3a-c。用FeCl_3氧化的化合物3a-c产生2-(5'-取代-2'-苯基吲哚-3'-基)-1-(香豆素-3“-酰胺基)氮杂环丁烷-2-酮5a-c。所有合成的化合物已对其抗菌活性进行了筛选。

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